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SEMI-BLIND SPATIALLY-VARIANT DECONVOLUTION IN OPTICAL MICROSCOPY WITH LOCAL POINT SPREAD FUNCTION ESTIMATION BY USE OF CONVOLUTIONAL NEURAL NETWORK

Abstract: 

We present a semi-blind, spatially-variant deconvolution technique aimed at optical microscopy that combines a local estimation step of the point spread function (PSF) and deconvolution using a spatially variant, regularized Richardson-Lucy algorithm. To find the local PSF map in a computationally tractable way, we train a convolutional neural network to perform regression of an optical parametric model on synthetically blurred image patches. We deconvolved both synthetic and experimentally-acquired data, and achieved an improvement of image SNR of 1.00 dB on average, compared to other deconvolution algorithms.

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Paper Details

Authors:
Michael Liebling
Submitted On:
6 October 2018 - 8:16pm
Short Link:
Type:
Poster
Event:
Presenter's Name:
Adrian Shajkofci
Paper Code:
WP.P9.1
Document Year:
2018
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Document Files

AS_ICIP2018_Poster_horiz.pdf

(12 downloads)

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[1] Michael Liebling, "SEMI-BLIND SPATIALLY-VARIANT DECONVOLUTION IN OPTICAL MICROSCOPY WITH LOCAL POINT SPREAD FUNCTION ESTIMATION BY USE OF CONVOLUTIONAL NEURAL NETWORK", IEEE SigPort, 2018. [Online]. Available: http://sigport.org/3580. Accessed: Nov. 19, 2018.
@article{3580-18,
url = {http://sigport.org/3580},
author = {Michael Liebling },
publisher = {IEEE SigPort},
title = {SEMI-BLIND SPATIALLY-VARIANT DECONVOLUTION IN OPTICAL MICROSCOPY WITH LOCAL POINT SPREAD FUNCTION ESTIMATION BY USE OF CONVOLUTIONAL NEURAL NETWORK},
year = {2018} }
TY - EJOUR
T1 - SEMI-BLIND SPATIALLY-VARIANT DECONVOLUTION IN OPTICAL MICROSCOPY WITH LOCAL POINT SPREAD FUNCTION ESTIMATION BY USE OF CONVOLUTIONAL NEURAL NETWORK
AU - Michael Liebling
PY - 2018
PB - IEEE SigPort
UR - http://sigport.org/3580
ER -
Michael Liebling. (2018). SEMI-BLIND SPATIALLY-VARIANT DECONVOLUTION IN OPTICAL MICROSCOPY WITH LOCAL POINT SPREAD FUNCTION ESTIMATION BY USE OF CONVOLUTIONAL NEURAL NETWORK. IEEE SigPort. http://sigport.org/3580
Michael Liebling, 2018. SEMI-BLIND SPATIALLY-VARIANT DECONVOLUTION IN OPTICAL MICROSCOPY WITH LOCAL POINT SPREAD FUNCTION ESTIMATION BY USE OF CONVOLUTIONAL NEURAL NETWORK. Available at: http://sigport.org/3580.
Michael Liebling. (2018). "SEMI-BLIND SPATIALLY-VARIANT DECONVOLUTION IN OPTICAL MICROSCOPY WITH LOCAL POINT SPREAD FUNCTION ESTIMATION BY USE OF CONVOLUTIONAL NEURAL NETWORK." Web.
1. Michael Liebling. SEMI-BLIND SPATIALLY-VARIANT DECONVOLUTION IN OPTICAL MICROSCOPY WITH LOCAL POINT SPREAD FUNCTION ESTIMATION BY USE OF CONVOLUTIONAL NEURAL NETWORK [Internet]. IEEE SigPort; 2018. Available from : http://sigport.org/3580