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VOICE BASED CLASSIFICATION OF PATIENTS WITH AMYOTROPHIC LATERAL SCLEROSIS, PARKINSON'S DISEASE AND HEALTHY CONTROLS WITH CNN-LSTM USING TRANSFER LEARNING

- Citation Author(s):
- Submitted by:
- Jhansi Mallela
- Last updated:
- 26 May 2020 - 1:39am
- Document Type:
- Presentation Slides
- Document Year:
- 2020
- Event:
- Presenters Name:
- Jhansi Mallela
- Paper Code:
- 4923
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Abstract
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In this paper, we consider 2-class and 3-class classification problemsfor classifying patients with Amyotropic Lateral Sclerosis (ALS),Parkinson’s Disease (PD) and Healthy Controls (HC) using a CNN-LSTM network. Classification performance is examined for threedifferent tasks, namely, Spontaneous speech (SPON), Diadochoki-netic rate (DIDK) and Sustained Phonation (PHON). Experimentsare conducted using speech data recorded from 60 ALS, 60 PD and60 HC subjects. Classification using SVM and DNN are consid-ered baseline schemes. Classification accuracy of ALS and HC (in-dicated by ALS/HC) using CNN-LSTM is found to be 89.20% forthe PHON task as compared to 78.80% using the best of the base-line schemes. Furthermore, the CNN-LSTM network achieves thehighest PD/HC classification accuracy of 88.5% for SPON task andthe highest 3-class (ALS/PD/HC) classification accuracy of 85.24%for DIDK task. Experiments using transfer learning at low resourcetraining data show that data from ALS benefits PD/HC classifica-tion and vice-versa. Experiments with fine-tuning weights of 3-class (ALS/PD/HC) classifier for 2-class classification (PD/HC orALS/HC) gives an absolute improvement of 2% classification accu-racy in SPON task when compared with randomly initialized 2-classclassifier.