We propose a convolutional neural network (CNN) aided factor graphs assisted by mutual information features estimated by a neural network for seizure detection. Specifically, we use neural mutual information estimation to evaluate the correlation between different electroencephalogram (EEG) channels as features. We then use a 1D-CNN to extract extra features from the EEG signals and use both features to estimate the probability of a seizure event. Finally, learned factor graphs are employed to capture the temporal correlation in the signal. Both sets of features from the neural mutual estimation and the 1D-CNN are used to learn the factor nodes. We show that the proposed method achieves state-of-the-art performance using 6-fold leave-four-patients-out cross-validation.