This paper proposes a method for depth estimation from a single multispectral image by using a lens property known as chromatic aberration. The natural refractive properties of lens known as chromatic aberration cause that the rays that are passing through the lens are refracted on different wavelengths differently depending on the wavelength-dependent refractive properties of the lens.It results in wavelength-dependent focal lengths due to the nature of refraction.The proposed method needs only a standard wide-aperture lens which naturally exhibits the chromatic aberration and a multispectral camera.In this paper, we show that the chromatic aberration provides depth information of a scene by assuming that its defocus blur is approximated as Gaussian blur. Moreover, we use a simple yet effective depth of field synthesis method to calculate the derivatives, which makes it possible to obtain all-in-focus images necessary for the approximation
of spectral derivatives. The effectiveness of the proposed method was verified on various real world challenging scenes.