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We introduce a novel, transient model for the electroencephalogram (EEG) as the noisy addition of linear filters responding to trains of delta functions. We set the synthesis part as a parameter-tuning problem and obtain synthetic EEG-like data that visually resembles brain activity in the time and frequency domains. For the analysis counterpart, we use sparse approximation to decompose the signal in relevant events via Matching Pursuit.


Protein fluxes provide a more refined notion of protein abundance than raw counts alone by considering potential channels based on protein interaction networks. We propose a novel method to estimate protein fluxes in a protein interaction network using a linear programming model based on the framework of flux balance analysis.


This paper is concerned with state estimation at a fixed time point in a given time series of observations of a Boolean dynamical system. Towards this end, we introduce the Boolean Kalman Smoother, which provides an efficient algorithm to compute the optimal MMSE state estimator for this problem. Performance is investigated using a Boolean network model of the p53-MDM2 negative feedback loop gene regulatory network observed through time series of Next-Generation Sequencing (NGS) data.