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Transcranial magnetic stimulation (TMS) is a non-invasive clinical technique used for treatment of several neurological diseases such as depression, Alzheimer’s disease and Parkinson’s disease. However, it is always challenging to accurately adjust the electric field on different specific brain regions due to the requirement of several stimulation parameters’ optimizations.

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One of the main difficulties in the use of deep learning strategies in medical contexts is the training set size. While these methods need large annotated training sets, this data is costly to obtain in medical contexts and suffers from intra and iter-subject variability.

In the present work, two new pre-processing techniques are introduced to improve a classifier performance. First, data augmentation based on co-registration is suggested. Then, multi-scale enhancement based on Difference of Gaussians is proposed.

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Most of the existing ultrasound image restoration methods consider a spatially-invariant point-spread function (PSF) model and circulant boundary conditions. While computationally efficient, this model is not realistic and severely limits the quality of reconstructed images. In this work, we address ultrasound image restoration under the hypothesis of vertical variation of the PSF. To regularize the solution, we use the classical elastic net constraint.

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Recent studies suggest that Resolution Enhancement Compression (REC) can provide significant improvements in terms of imaging quality over Classical Pulsed (CP) ultrasonic imaging techniques, by employing frequency and amplitude modulated transmitted signals. However the performance of coded excitations methods degrades drastically deeper into the tissue where the attenuation effects become more significant. In this work, a technique that allows overcoming the effects of attenuation on REC imaging is proposed (REC-Opt).

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Medical research suggests that the area of the IVC and its temporal variation imaged by bedside ultrasound is useful in guiding resuscitation of the critically-ill. Unfortunately, gaps in the vessel wall and intraliminal artifact represents a challenge for both manual and existing algorithm-based segmentation techniques.

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Analyzing the asymmetry of anatomical shapes is one of the cornerstones of efficient computerized diagnosis. In the application of scoliotic trunk analysis, one major challenge is the high variability and complexity of deformations due to the pathology itself, and to changes of body poses, for instance, torsos acquired in lateral bending poses for surgical planning. In this paper, we present a novel and fully automatic approach to analyzing the asymmetry of deformable trunk shapes.

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